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What mg will my shortfill be if i add one 18mg nicotine shot?

One 18mg nicotine shot in your 50ml shortfill will give you a 3mg (Make sure you shake well before use) For the same results in a 100ml shortfill add two nicotine shots.

Can i make my shortfill 6mg or more using nicotine shots?

There is no rule to say you cant add more nicotine shots to your eliquid, But bare it in mind that most eliquids are designed for one nicotine shot. So adding more may dillute the desired flavour.